Single-Arm Phases 1 and 2 Trial of Niraparib in Combination With Pembrolizumab in Patients With Recurrent Platinum-Resistant Ovarian Carcinoma

Author:

Konstantinopoulos Panagiotis A.12,Waggoner Steven3,Vidal Gregory A.4,Mita Monica5,Moroney John W.6,Holloway Robert78,Van Le Linda9,Sachdev Jasgit C.1011,Chapman-Davis Eloise12,Colon-Otero Gerardo13,Penson Richard T.14,Matulonis Ursula A.15,Kim Young Bae16,Moore Kathleen N.1718,Swisher Elizabeth M.19,Färkkilä Anniina20,D’Andrea Alan21,Stringer-Reasor Erica22,Wang Jing23,Buerstatte Nathan24,Arora Sujata25,Graham Julie R.26,Bobilev Dmitri26,Dezube Bruce J.26,Munster Pamela27

Affiliation:

1. Division of Gynecologic Oncology, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts

2. Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts

3. Department of Reproductive Medicine, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, Cleveland, Ohio

4. Division of Medical Oncology, West Cancer Center, Memphis, Tennessee

5. Department of Hematology and Oncology, Cedars-Sinai Medical Center, Los Angeles, California

6. Section of Gynecologic Oncology, Department of Obstetrics & Gynecology, University of Chicago Medicine, Chicago, Illinois

7. Division of Gynecologic Oncology, Florida Hospital Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando

8. Global Robotics Institute, Orlando, Florida

9. Department of Obstetrics & Gynecology, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill

10. Division of Hematology and Oncology, Virginia G. Piper Cancer Center Clinical Trials, HonorHealth Research Institute, Scottsdale, Arizona

11. Translational Genomics Research Institute, Scottsdale, Arizona

12. Weill Cornell Medicine, Department of Obstetrics and Gynecology, Cornell University, New York, New York

13. Department of Internal Medicine, Mayo Clinic, Jacksonville, Florida

14. Division of Hematology-Oncology, Department of Medicine, Massachusetts General Hospital, Boston

15. Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts

16. Department of Obstetrics and Gynecology, Tufts Medical Center, Boston, Massachusetts

17. Stephenson Cancer Center, Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City

18. Sarah Cannon Research Institute, Nashville, Tennessee

19. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington, Seattle

20. Department of Obstetrics and Gynaecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland

21. Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts

22. Division of Hematology/Oncology, Department of Medicine, The University of Alabama at Birmingham

23. Department of Research & Early Development, TESARO: A GSK Company, Waltham, Massachusetts

24. Department of Clinical Operations, TESARO: A GSK Company, Waltham, Massachusetts

25. Department of Biostatistics, TESARO: A GSK Company, Waltham, Massachusetts

26. Department of Clinical Science, TESARO: A GSK Company, Waltham, Massachusetts

27. Helen Diller Family Comprehensive Cancer Center, Department of Medicine, University of California, San Francisco, Medical Center at Mount Zion, San Francisco

Publisher

American Medical Association (AMA)

Subject

Oncology,Cancer Research

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