Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis

Author:

Chen Hao Yu12,Cairns Benjamin J.345,Small Aeron M.6,Burr Hannah A.12,Ambikkumar Athithan2,Martinsson Andreas78,Thériault Sébastien9,Munter Hans Markus10,Steffen Brian11,Zhang Richard2,Levinson Rebecca T.12,Shaffer Christian M.12,Rong Jian1314,Sonestedt Emily15,Dufresne Line2,Ljungberg Johan16,Näslund Ulf16,Johansson Bengt16,Ranatunga Dilrini K.17,Whitmer Rachel A.18,Budoff Matthew J.1920,Nguyen Albert2,Vasan Ramachandran S.1314,Larson Martin G.1314,Harris William S.2122,Damrauer Scott M.23,Stark Ken D.24,Boekholdt S. Matthijs25,Wareham Nicholas J.26,Pibarot Philippe9,Arsenault Benoit J.9,Mathieu Patrick9,Gudnason Vilmundur27,O’Donnell Christopher J.1314,Rotter Jerome I.1920,Tsai Michael Y.11,Post Wendy S.28,Clarke Robert345,Söderberg Stefan16,Bossé Yohan9,Wells Quinn S.12,Smith J. Gustav82930,Rader Daniel J.316,Lathrop Mark1032,Engert James C.1232,Thanassoulis George12

Affiliation:

1. Division of Experimental Medicine, McGill University, Montreal, Quebec, Canada

2. Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada

3. MRC (Medical Research Council) Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

4. Clinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

5. Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

6. Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia

7. Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden

8. Department of Cardiology, Skåne University Hospital, Lund, Sweden

9. Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada

10. McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada

11. Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota

12. Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University Medical Center, Nashville, Tennessee

13. National Heart, Lung, and Blood Institute, Bethesda, Maryland

14. Boston University’s Framingham Heart Study, Boston, Massachusetts

15. Nutritional Epidemiology, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden

16. Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden

17. Division of Research, Kaiser Permanente of Northern California, Oakland

18. Department of Public Health Sciences, University of California, Davis

19. Los Angeles Biomedical Research Institute, Torrance, California

20. Departments of Pediatrics and Medicine at Harbor-UCLA (University of California, Los Angeles) Medical Center, Torrance

21. Department of Medicine, Sanford School of Medicine, University of South Dakota, Sioux Falls, South Dakota

22. OmegaQuant Analytics LLC, Sioux Falls, South Dakota

23. Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia

24. Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada

25. Department of Cardiology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands

26. MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom

27. Faculty of Medicine, University of Iceland, Reykjavík

28. Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland

29. Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden

30. Lund University Diabetes Center, Lund University, Lund, Sweden

31. Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia

32. Department of Human Genetics, McGill University, Montreal, Quebec, Canada

Publisher

American Medical Association (AMA)

Subject

Cardiology and Cardiovascular Medicine

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