Rationale and Design of the Aspirin Dosing—A Patient-Centric Trial Assessing Benefits and Long-term Effectiveness (ADAPTABLE) Trial

Author:

Marquis-Gravel Guillaume1,Roe Matthew T.12,Robertson Holly R.1,Harrington Robert A.3,Pencina Michael J.4,Berdan Lisa G.1,Hammill Bradley G.1,Faulkner Madelaine5,Muñoz Daniel6,Fonarow Gregg C.78,Nallamothu Brahmajee K.9,Fintel Dan J.10,Ford Daniel E.11,Zhou Li12,Daugherty Sarah E.13,Nauman Elizabeth14,Kraschnewski Jennifer15,Ahmad Faraz S.16,Benziger Catherine P.17,Haynes Kevin18,Merritt J. Greg19,Metkus Thomas2021,Kripalani Sunil22,Gupta Kamal23,Shah Raj C.24,McClay James C.25,Re Richard N.26,Geary Carol27,Lampert Brent C.28,Bradley Steven M.29,Jain Sandeep K.30,Seifein Hani31,Whittle Jeff32,Roger Véronique L.33,Effron Mark B.34,Alvarado Giselle35,Goldberg Ythan H.36,VanWormer Jeffrey L.37,Girotra Saket38,Farrehi Peter39,McTigue Kathleen M.40,Rothman Russell41,Hernandez Adrian F.12,Jones W. Schuyler12

Affiliation:

1. Duke Clinical Research Institute, Durham, North Carolina

2. Duke University Medical Center, Durham, North Carolina

3. Department of Medicine, Stanford University, Stanford, California

4. Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina

5. Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco

6. Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee

7. Department of Medicine, University of California, Los Angeles, Los Angeles

8. Associate Editor, JAMA Cardiology

9. Michigan Integrated Center of Health Analytics and Medical Prediction, Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor

10. Feinberg School of Medicine, Division of Cardiology, Department of Medicine, Northwestern University, Chicago, Illinois

11. Johns Hopkins University School of Medicine, Baltimore, Maryland

12. Wake Forest University School of Medicine, Winston-Salem, North Carolina

13. Patient-Centered Outcomes Research Institute, Washington, DC

14. Louisiana Public Health Institute, New Orleans

15. Department of Medicine, Department of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania

16. Center for Health Information Partnerships, Feinberg School of Medicine, Institute of Public Health and Medicine, Division of Cardiology, Department of Medicine, Northwestern University, Chicago, Illinois

17. Essentia Health Heart and Vascular Center, Duluth, Minnesota

18. HealthCore Inc, Wilmington, Delaware

19. Patient-Centered Network of Learning Health Systems (LHSNet), Ann Arbor, Michigan

20. Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland

21. Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland

22. Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee

23. Division of Cardiovascular Medicine, Department of Medicine, University of Kansas Medical Center, Kansas City

24. Rush Alzheimer's Disease Center, Department of Family Medicine, Rush University Medical Center, Chicago, Illinois

25. Department of Emergency Medicine, University of Nebraska Medical Center College of Medicine, Omaha

26. Ochsner Health System, New Orleans, Louisiana

27. University of Nebraska Medical Center, Omaha

28. Wexner Medical Center, Division of Cardiovascular Medicine, The Ohio State University, Columbus

29. Minneapolis Heart Institute, Minneapolis Heart Institute Foundation, Minneapolis

30. UPMC Heart and Vascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

31. AdventHealth Medical Group Cardiology, Oviedo, Florida

32. Department of Medicine, Division of General Internal Medicine, Medical College of Wisconsin, Milwaukee

33. Mayo Clinic, Rochester, Minnesota

34. Ochsner Clinical School, John Ochsner Heart and Vascular Institute, University of Queensland School of Medicine, New Orleans, Louisiana

35. Herbert H. Lehman College, Department of Biological Sciences, City University of New York, Bronx

36. Albert Einstein College of Medicine, Bronx, New York

37. Marshfield Clinic Research Institute, Marshfield, Wisconsin

38. Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City

39. University of Michigan Medical School, Ann Arbor

40. University of Pittsburgh, Pittsburgh, Pennsylvania

41. Center for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee

Publisher

American Medical Association (AMA)

Subject

Cardiology and Cardiovascular Medicine

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