Results of a Remotely Delivered Hypertension and Lipid Program in More Than 10 000 Patients Across a Diverse Health Care Network

Author:

Blood Alexander J.12,Cannon Christopher P.12,Gordon William J.234,Mailly Charlotte4,MacLean Taylor1,Subramaniam Samantha1,Tucci Michela1,Crossen Jennifer15,Nichols Hunter15,Wagholikar Kavishwar B.6,Zelle David1,McPartlin Marian1,Matta Lina S.5,Oates Michael4,Aronson Samuel4,Murphy Shawn2678,Landman Adam29,Fisher Naomi D. L.210,Gaziano Thomas A.12,Plutzky Jorge12,Scirica Benjamin M.12

Affiliation:

1. Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Boston, Massachusetts

2. Harvard Medical School, Boston, Massachusetts

3. Division of General Medicine, Brigham and Women’s Hospital, Boston, Massachusetts

4. Mass General Brigham Personalized Medicine, Boston, Massachusetts

5. Department of Pharmacy Services, Brigham and Women’s Hospital, Boston, Massachusetts

6. Laboratory of Computer Science, Massachusetts General Hospital, Boston

7. Department of Neurology, Massachusetts General Hospital, Boston

8. Research Information Science and Computing, Mass General Brigham, Boston, Massachusetts

9. Department of Emergency Medicine, Brigham and Women’s Hospital, Boston, Massachusetts

10. Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital, Boston, Massachusetts

Abstract

ImportanceBlood pressure (BP) and cholesterol control remain challenging. Remote care can deliver more effective care outside of traditional clinician-patient settings but scaling and ensuring access to care among diverse populations remains elusive.ObjectiveTo implement and evaluate a remote hypertension and cholesterol management program across a diverse health care network.Design, Setting, and ParticipantsBetween January 2018 and July 2021, 20 454 patients in a large integrated health network were screened; 18 444 were approached, and 10 803 were enrolled in a comprehensive remote hypertension and cholesterol program (3658 patients with hypertension, 8103 patients with cholesterol, and 958 patients with both). A total of 1266 patients requested education only without medication titration. Enrolled patients received education, home BP device integration, and medication titration. Nonlicensed navigators and pharmacists, supported by cardiovascular clinicians, coordinated care using standardized algorithms, task management and automation software, and omnichannel communication. BP and laboratory test results were actively monitored.Main Outcomes and MeasuresChanges in BP and low-density lipoprotein cholesterol (LDL-C).ResultsThe mean (SD) age among 10 803 patients was 65 (11.4) years; 6009 participants (56%) were female; 1321 (12%) identified as Black, 1190 (11%) as Hispanic, 7758 (72%) as White, and 1727 (16%) as another or multiple races (including American Indian or Alaska Native, Asian, Native Hawaiian or Other Pacific Islander, unknown, other, and declined to respond; consolidated owing to small numbers); and 142 (11%) reported a preferred language other than English. A total of 424 482 BP readings and 139 263 laboratory reports were collected. In the hypertension program, the mean (SD) office BP prior to enrollment was 150/83 (18/10) mm Hg, and the mean (SD) home BP was 145/83 (20/12) mm Hg. For those engaged in remote medication management, the mean (SD) clinic BP 6 and 12 months after enrollment decreased by 8.7/3.8 (21.4/12.4) and 9.7/5.2 (22.2/12.6) mm Hg, respectively. In the education-only cohort, BP changed by a mean (SD) −1.5/−0.7 (23.0/11.1) and by +0.2/−1.9 (30.3/11.2) mm Hg, respectively (P < .001 for between cohort difference). In the lipids program, patients in remote medication management experienced a reduction in LDL-C by a mean (SD) 35.4 (43.1) and 37.5 (43.9) mg/dL at 6 and 12 months, respectively, while the education-only cohort experienced a mean (SD) reduction in LDL-C of 9.3 (34.3) and 10.2 (35.5) mg/dL at 6 and 12 months, respectively (P < .001). Similar rates of enrollment and reductions in BP and lipids were observed across different racial, ethnic, and primary language groups.Conclusions and RelevanceThe results of this study indicate that a standardized remote BP and cholesterol management program may help optimize guideline-directed therapy at scale, reduce cardiovascular risk, and minimize the need for in-person visits among diverse populations.

Publisher

American Medical Association (AMA)

Subject

Cardiology and Cardiovascular Medicine

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