Clinical and Functional Characterization of Ryanodine Receptor 2 Variants Implicated in Calcium-Release Deficiency Syndrome

Author:

Roston Thomas M.12,Wei Jinhong3,Guo Wenting3,Li Yanhui3,Zhong Xiaowei3,Wang Ruiwu3,Estillore John Paul3,Peltenburg Puck J.4,Noguer Ferran Rosés I.5,Till Jan5,Eckhardt Lee L.6,Orland Kate M.6,Hamilton Robert7,LaPage Martin J.8,Krahn Andrew D.2,Tadros Rafik9,Vinocur Jeffrey M.1011,Kallas Dania12,Franciosi Sonia12,Roberts Jason D.1314,Wilde Arthur A. M.415,Jensen Henrik K.1617,Sanatani Shubhayan12,Chen S. R. Wayne3

Affiliation:

1. Division of Cardiology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada

2. Centre for Cardiovascular Innovation, Division of Cardiology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

3. Libin Cardiovascular Institute, Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada

4. Department of Clinical and Experimental Cardiology, Heart Center, Amsterdam University Medical Centre, Amsterdam, the Netherlands

5. Department of Cardiology, Royal Brompton Hospital, London, United Kingdom

6. Division of Cardiovascular Medicine, University of Wisconsin, Madison

7. Division of Cardiology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada

8. Division of Cardiology, Department of Pediatrics, University of Michigan, Ann Arbor

9. Division of Cardiology, Montreal Heart Institute, University of Montreal, Montreal, Québec, Canada

10. Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada

11. currently affiliated with Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut

12. Children’s Heart Centre, Division of Cardiology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada

13. Section of Cardiac Electrophysiology, Division of Cardiology, Western University, London, Ontario, Canada

14. now affiliated with Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada

15. Member of the European Reference Network ERN GUARD-Heart

16. Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark

17. Department of Medicine, Aarhus University, Aarhus, Denmark

Publisher

American Medical Association (AMA)

Subject

Cardiology and Cardiovascular Medicine

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