Seaweed-Derived Sulfated Polysaccharides as Potential Agents for Prevention and Treatment of Inﬂuenza and COVID-19-Reference-Cited by-同舟云学术

Seaweed-Derived Sulfated Polysaccharides as Potential Agents for Prevention and Treatment of Inﬂuenza and COVID-19

Published:2021-10-21 Issue:7-8 Volume:66 Page:50-66
ISSN:0235-2990
Container-title:Antibiotics and Chemotherapy
language:
Short-container-title:A&Ch

Author:

Besednova N. N.¹^ORCID,Zvyagintseva T. N.²,Andriukov B. G.¹^ORCID,Zaporozhets T. S.¹,Kuznetsova T. A.¹^ORCID,Kryzhanovsky S. P.³,Guseva L. G.³,Shchelkanov M. Yu.⁴^ORCID

Affiliation:

1. Research Institute of Epidemiology and Microbiology named after G. P. Somov

2. G.B. Elyakov Paciﬁc Institute of Bioorganic Chemistry, Far Eastern Branch of Russian Academy of Sciences

3. Medical Association of the Far Eastern Branch of the Russian Academy of Sciences

4. Research Institute of Epidemiology and Microbiology named after G. P. Somov; Federal Scientiﬁc Center of the Eastern Asia Terrestrial Biodiversity, Far Eastern Branch of Russian Academy of Sciences; National Scientiﬁc Center of Marine Biology, Far Eastern Branch of Russian Academy of Sciences

Abstract

The review presents materials describing the seaweed-derived sulfated polysaccharides (SPS) as potential means for prevention and treatment of viral diseases of the respiratory tract, mainly inﬂuenza and COVID-19. The literature materials on the pathogenetic targets of inﬂuenza viruses and SARS-CoV-2, on the antiviral potential of SPS derived from red, brown and green algae, as well as on the mechanisms of antiviral action of these unique compounds are summarized. Seaweed SPS are characterized by high antiviral activity, good solubility, and almost complete absence of toxicity. Pathogens of respiratory infections do not form resistance under the SPS inﬂuence. The abovementioned facts allow us to consider these compounds as promising candidates for the creation of medicines, dietary supplements, and functional food products with antiviral and, above all, anti-inﬂuenza and anti-coronavirus activity on their basis in the future.

Publisher

Publishing House OKI

Subject

Infectious Diseases,Microbiology (medical),General Medicine,Microbiology

Reference118 articles.

1. Breitbart M., Rohwer F. Here a virus, there a virus, everywhere the same virus? Trends Microbiol. 2005; 13 (6): 278–84. doi: 10/1016/j.tim.2005.04.003.

2. Rukovodstvo po virusologii. Virusy i virusnye infektsii cheloveka i zhivotnykh. Red.: D.K. L'vova. M.: MIA, 2013; 1200. (in Russian)

3. Lvov D.K., Shchelkanov M.Yu., Alkhovsky S.V., Deryabin P.G. Zoonotic viruses of Northern Eurasia. Taxonomy and Ecology. Academic Press, 2015; 452.

4. Pagarete A., Ramos A.S., Puntervoll P. et al. Antiviral potential of algal metabolites — a comprehensive review. Mar Drugs. 2021; 19 (2): 94.

5. Virusnye infektsii dykhatel'nykh putej. V kn.: Pul'monologiya. Natsional'noe Rukovodstvo. Red.: A.G. Chuchalin. Moscow: GEOTAR-Media, 2016; 143–170. (in Russian)

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