Higher Magnesium Intake Is Associated with Lower Fasting Glucose and Insulin, with No Evidence of Interaction with Select Genetic Loci, in a Meta-Analysis of 15 CHARGE Consortium Studies

Author:

Hruby Adela1,Ngwa Julius S.2,Renström Frida345,Wojczynski Mary K.6,Ganna Andrea7,Hallmans Göran8,Houston Denise K.9,Jacques Paul F.1,Kanoni Stavroula1011,Lehtimäki Terho12,Lemaitre Rozenn N.13,Manichaikul Ani14,North Kari E.15,Ntalla Ioanna16,Sonestedt Emily4,Tanaka Toshiko16,van Rooij Frank J. A.1718,Bandinelli Stefania19,Djoussé Luc20,Grigoriou Efi11,Johansson Ingegerd21,Lohman Kurt K.22,Pankow James S.23,Raitakari Olli T.24,Riserus Ulf25,Yannakoulia Mary11,Zillikens M. Carola171826,Hassanali Neelam27,Liu Yongmei28,Mozaffarian Dariush29,Papoutsakis Constantina11,Syvänen Ann-Christine30,Uitterlinden André G.171826,Viikari Jorma31,Groves Christopher J.27,Hofman Albert1718,Lind Lars32,McCarthy Mark I.2733,Mikkilä Vera34,Mukamal Kenneth35,Franco Oscar H.1718,Borecki Ingrid B.6,Cupples L. Adrienne236,Dedoussis George V.11,Ferrucci Luigi16,Hu Frank B.3,Ingelsson Erik7,Kähönen Mika37,Kao W. H. Linda38,Kritchevsky Stephen B.9,Orho-Melander Marju4,Prokopenko Inga2739,Rotter Jerome I.40,Siscovick David S.1341,Witteman Jacqueline C. M.1718,Franks Paul W.345,Meigs James B.42,McKeown Nicola M.1,Nettleton Jennifer A.43

Affiliation:

1. Tufts University Friedman School of Nutrition Science and Policy, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA

2. Department of Biostatistics, Boston University School of Public Health, Boston, MA

3. Department of Nutrition, Harvard School of Public Health, Boston, MA

4. Department of Clinical Sciences, Lund University, Malmö, Sweden

5. Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden

6. Department of Genetics, Washington University School of Medicine, St. Louis, MO

7. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

8. Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, Umeå, Sweden

9. Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC

10. Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK

11. Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece

12. Fimlab Laboratories and University of Tampere, School of Medicine, and Tampere University Hospital, Tampere, Finland

13. Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA

14. Center for Public Health Genomics, and Division of Biostatistics and Epidemiology, Department of Public Health Sciences, University of Virginia, Charlottesville, VA

15. Department of Epidemiology and Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC

16. Clinical Research Branch, National Institute on Aging, Baltimore, MD

17. Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands

18. Netherlands Genomics Initiative-sponsored Netherlands Consortium for Healthy Aging, Leiden, The Netherlands

19. Geriatric Unit, Azienda Sanitaria Firenze, Florence, Italy

20. Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Massachusetts Veterans Epidemiology and Research Information Center and Geriatric Research, Education, and Clinical Center, Boston Veterans Affairs Healthcare System, Boston, MA

21. Department of Odontology, Umeå University, Umeå, Sweden

22. Division of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC

23. Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN

24. Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, and Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland

25. Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden

26. Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

27. Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK

28. Division of Public Health Sciences, Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC

29. Department of Epidemiology and Nutrition, Harvard School of Public Health, Boston, MA; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

30. Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden

31. Department of Medicine, University of Turku, and Turku University Hospital, Turku, Finland

32. Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden

33. Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, UK

34. Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland

35. Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, MA

36. Framingham Heart Study, Framingham, MA

37. Department of Clinical Physiology, Tampere University Hospital, and University of Tampere, Tampere, Finland

38. Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD

39. Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK

40. Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, CA

41. Department of Epidemiology, University of Washington, Seattle, WA

42. Harvard Medical School and General Medicine Division, Clinical Epidemiology and Diabetes Research Units, Massachusetts General Hospital, Boston, MA

43. Division of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health at The University of Texas Health Science Center–Houston, Houston, TX

Publisher

Oxford University Press (OUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

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