Author:
ADAMS C. W. M.,PEARSE A. G. EVERSON
Abstract
SUMMARY
1. Two types of mucoid (basophil) cell, described as R and S, can be distinguished in the human adenohypophysis by a performic acid-Alcian blue method for cystine.
2. The relationship of the S—R terminology to other nomenclatures of human pituitary basophils is discussed.
3. The R cell, which contains little cystine, is the common mucoid cell of the human adenohypophysis: it is the cell which undergoes hyalinization in Cushing's syndrome and after cortisone therapy.
4. The S cell is found in the normal pituitary and, in great numbers, in Addison's disease and in shock: it is suggested that this cell is responsible for corticotrophin-synthesis.
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Cited by
45 articles.
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