SRD005825 Acts as a Pharmacologic Chaperone of Opsin and Promotes Survival of Photoreceptors in an Animal Model of Autosomal Dominant Retinitis Pigmentosa
Author:
Affiliation:
1. Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL, USA
2. Shire HGT Inc., a member of the Takeda group of companies, Cambridge, MA, USA
3. Covance Inc., Madison, WI, USA
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Subject
Ophthalmology,Biomedical Engineering
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2. Rhodopsin-associated retinal dystrophy: Disease mechanisms and therapeutic strategies;Frontiers in Neuroscience;2023-04-03
3. Pharmacological Chaperones;Protein Homeostasis in Drug Discovery;2022-11-14
4. Nonretinoid chaperones improve rhodopsin homeostasis in a mouse model of retinitis pigmentosa;JCI Insight;2022-05-23
5. Gene Therapy of Dominant CRX-Leber Congenital Amaurosis using Patient Stem Cell-Derived Retinal Organoids;Stem Cell Reports;2021-02
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