Adeno-Associated Virus–Mediated IL-10 Gene Transfer Suppresses Lacrimal Gland Immunopathology in a Rabbit Model of Autoimmune Dacryoadenitis

Author:

Thomas Padmaja B.1,Samant Deedar M.1,Selvam Shivaram1,Wei Rui Hua1,Wang Yanru2,Stevenson Douglas1,Schechter Joel E.3,Apparailly Florence4,Mircheff Austin K.5,Trousdale Melvin D.6

Affiliation:

1. From the Ocular Surface Center, Doheny Eye Institute, Los Angeles, California;

2. the Departments of Physiology and Biophysics,

3. From the Ocular Surface Center, Doheny Eye Institute, Los Angeles, California; 3Ophthalmology, and 4Cell and Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, California;

4. Inserm, U844, Hospital St. Eloi, Montpellier, France; 6Université Montpellier 1, UFR de Médecine, Montpellier, France; and 7CHU Lapeyronie, Service Immuno-Rhumatologie, Montpellier, France.

5. From the Ocular Surface Center, Doheny Eye Institute, Los Angeles, California; the Departments of 2Physiology and Biophysics, 3Ophthalmology, and

6. From the Ocular Surface Center, Doheny Eye Institute, Los Angeles, California; 3Ophthalmology, and

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

General Medicine

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