Affiliation:
1. Clinic Lung Physiology Hospital; Transilvania University of Brasov
2. Smolensk State Medical University
Abstract
Immunology is a branch of medicine that studies the immune system and its pathology. There are known scientific information, that in medical immunology specific tests performed in the laboratory for diagnosis. In addition, good to mention that allergies include medical diagnostic methods such as blood tests. Also, there are used for detection the presence and the levels of IgE antibodies. Currently within the present description aim to discuss some aspects referring to fungal allergen and mold allergy diagnosis, in a shortage following steps of our purposed description.Molds produce mycotoxins, unfortunately with carcinogenic, teratogenic and neurotoxic properties, with a possible negative impact on individual healthy. Allergies related to fungi together with comorbidities, mainly concern immunocompromised patients. The currently describing knowledges in the field of allergy between fungal allergens and human subjects, and also established the diagnosis and treatment, offer us a complex vision. For the future, hope to find into the research studies, proper knowledges in this field, with applicability in routine practice.
Publisher
Karaganda Medical University
Reference49 articles.
1. A double-blind, multicenter immunotherapy trial in children, using a purified and standardized Cladosporium herbarum preparation I /S. Dreborg, B. Agrell, T. Foucard //Clinical results. Allergy. – 1986. – V. 41 (2). – P. 131-140.
2. Aalberse R. C. Structural biology of allergens //J. Allergy Clin. Immunol. – 2000. – V. 106. – P. 228-238.
3. Allergens produce serine proteasesdependent distinct release of metabolite DAMPs in human bronchial epithelial cells /S. Ramu, M. Menzel, L. Bjermer //Clin. Exp. Allergy. – 2018. – V. 48 (2). – P. 156-166.
4. Allergic Fungal Airway Disease /E. M. Rick, K. Woolnough, C. H. Pashley, A. J. Wardlaw // J. Investig. Allergol. Clin. Immunol. – 2016. – V. 26 (6). P. 344-354.
5. Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the world health organization, GA(2)LEN and llerGen) / J. Bousquet, N. Khaltaev, A. A. Cruz et al. //Allergy. – 2008. – V. 63, Suppl. 86. – P. 8-16.