Concurrent chemoradiation therapy for improving survival in older patients with glioblastoma: a narrative review

Abstract

Despite the establishment of standard treatments for glioblastoma, the efficacy of concurrent chemoradiation therapy (CCRT) for older patients remains a matter of debate, even with the insights from recent randomized trials. This study offers an updated, evidence-based review of contemporary management using CCRT in older glioblastoma patients. Treating older glioblastoma patients necessitates a tailored approach, prioritizing individual patient needs. Additionally, this study emphasizes the efficacy of short-course CCRT, which has been confirmed through recent randomized trials.