Non-invasive Brain Stimulation and Prism Adaptation in Art Constructive Errors of Painting

Abstract

Introduction: This study aimed to investigate the influence of neglect and the effect of Prism Adaptation (PA) combined with continuous Theta-Burst Transcranial Magnetic Stimulation (cTBS) on the art constructive errors of painting rehabilitation of stroke patients with neglect. Methods: Fourteen patients with neglect and art constructive errors of painting secondary to stroke were randomly assigned to the rehabilitation group and received PA combined with inhibitory protocol of cTBS over the intact parietal cortex; the control group received PA combined with sham cTBS for 2 weeks in 10 daily sessions. Patients have assessed for art constructive errors of painting in Figure Copying Test (FCT), and Coloring Test (CT) before and after the intervention. Art constructive errors of painting were classified into omission, deformation, size, neglect of warm colors, and perseveration of errors. Neglect was evaluated using the Line Bisection task (LBT), Figure Copying Test (FCT), and Coloring Test (CT). Results: All patients showed significant improvement in art constructive errors of painting (measured using pattern of painting’ errors in Figure Copying Test and Coloring Test), and neglect (measured using LBT, FCT, and CT) (p<0.05). Omission, neglect of warm colors, and deformation were the most frequent errors. Conclusion: Neglect and rehabilitation influences the painting system in stroke patients. Both approaches improved art constructive errors of painting and neglect symptoms.