1. Department of Gastroenterology, Nagasaki Harbor Medical Center, Nagasaki 850‑8555, Japan
2. Innovation and Translational Research Center, Nagasaki Harbor Medical Center, Nagasaki 850‑8555, Japan
3. Department of Gastroenterology and Hepatology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852‑8501, Japan