Targeting of STAT5 using the small molecule topotecan hydrochloride suppresses acute myeloid leukemia progression

Author:

Li Jiahui1,Tang Bin2,Miao Ying3,Li Guihong4,Sun Zhenliang1

Affiliation:

1. Fengxian Hospital Affiliated to Anhui University of Science and Technology, Shanghai 201499, P.R. China

2. Department of Gynecology, East China Normal University Wuhu Affiliated Hospital (The Second People's Hospital of Wuhu City), Wuhu, Anhui 241000, P.R. China

3. East China Normal University and Shanghai Fengxian District Central Hospital Joint Center for Translational Medicine, Shanghai Key Laboratory of Regulatory Biology Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 201100, P.R. China

4. Fengxian Hospital Affiliated to The Southern Medical University, Shanghai 201499, P.R. China

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology,General Medicine

Reference47 articles.

1. Acute myeloid leukemia;Döhner;N Engl J Med,2015

2. Cancer stat facts: Leukemia-acute myeloid leukemia;National Cancer Institute (NCI),2020

3. Cancer statistics, 2021;Siegel;CA Cancer J Clin,2021

4. Survival and cure of acute myeloid leukaemia in England, 1971–2006: A population-based study;Shah;Br J Haematol,2013

5. Outcome of older patients with acute myeloid leukemia: An analysis of SEER data over 3 decades;Thein;Cancer,2013

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1. JAK/STAT in leukemia: a clinical update;Molecular Cancer;2024-01-26

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