Subacute paraneoplastic neuropathy as a form of “classic” paraneoplastic syndrome (literature review)

Abstract

The article reviews the problem of paraneoplastic neurological syndromes with a focus on paraneoplastic subacute neuropathy. It outlines clinical manifestations, diagnostic criteria of the 2021 PNS-Care Score, recommended methods of patients’ examination and treatment for paraneoplastic sensory neuropathies. The relevance of this article is driven by the overall increase in cancers in the population and, consequently, the rise in the frequency of paraneoplastic syndromes. Given that paraneoplastic syndromes can arise at any stage of oncological disease, both in diagnosed cancer and in preclinical stages preceding the detection of primary cancer, a review of this topic is beneficial for early diagnosis and improvement of treatment outcomes.