Poncirin Inhibits Osteoclast Differentiation and Bone Loss through Down-Regulation of NFATc1 In Vitro and In Vivo-Reference-Cited by-同舟云学术

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Poncirin Inhibits Osteoclast Differentiation and Bone Loss through Down-Regulation of NFATc1 In Vitro and In Vivo

Published:2020-07-01 Issue:4 Volume:28 Page:337-343
ISSN:1976-9148
Container-title:Biomolecules & Therapeutics
language:en
Short-container-title:Biomolecules & Therapeutics

Author:

Chun Kwang-Hoon¹,Jin Hyun Chul²,Kang Ki Sung²,Chang Tong-Shin³,Hwang Gwi Seo²

Affiliation:

1. Gachon Institute of Pharmaceutical Sciences, College of Pharmacy, Gachon University, Incheon 21936, Republic of Korea

2. Lab of Cell Differentiation Research, College of Oriental Medicine, Gachon University, Seongnam 13120, Republic of Korea

3. College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea

Funder

Gachon University

Publisher

The Korean Society of Applied Pharmacology

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pdf.medrang.co.kr/BT2/2020/028/BT028-04-06.pdf

Reference32 articles.

1. Autoamplification of NFATc1 expression determines its essential role in bone homeostasis

2. Osteoclast differentiation and activation

3. Anti-osteoclastogenic activity of matairesinol via suppression of p38/ERK-NFATc1 signaling axis

4. The Fos-related antigen Fra-1 is an activator of bone matrix formation

5. Receptor activator of NF-κB ligand induces the expression of carbonic anhydrase II, cathepsin K, and matrix metalloproteinase-9 in osteoclast precursor RAW264.7 cells

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