Coupling of Airway Smooth Muscle Bitter Taste Receptors to Intracellular Signaling and Relaxation Is via Gαi1,2,3-Reference-Cited by-同舟云学术

Coupling of Airway Smooth Muscle Bitter Taste Receptors to Intracellular Signaling and Relaxation Is via Gαi1,2,3

Published:2017-06 Issue:6 Volume:56 Page:762-771
ISSN:1044-1549
Container-title:American Journal of Respiratory Cell and Molecular Biology
language:en
Short-container-title:Am J Respir Cell Mol Biol

Author:

Kim Donghwa¹,Woo Jung A.¹,Geffken Ezekiel²,An Steven S.²,Liggett Stephen B.³

Affiliation:

1. Department of Medicine and the Center for Personalized Medicine and Genomics, University of South Florida Morsani College of Medicine, Tampa, Florida

2. Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; and

3. Departments of Internal Medicine and Molecular Pharmacology and Physiology, and the Center for Personalized Medicine and Genomics, University of South Florida Morsani College of Medicine, Tampa, Florida

Publisher

American Thoracic Society

Subject

Cell Biology,Clinical Biochemistry,Pulmonary and Respiratory Medicine,Molecular Biology

Link

http://www.atsjournals.org/doi/pdf/10.1165/rcmb.2016-0373OC

Reference43 articles.

1. The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors

2. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction

3. Agonist-Promoted Homologous Desensitization of Human Airway Smooth Muscle Bitter Taste Receptors

4. The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea

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