Affiliation:
1. Branch of the Private Educational Institution of Higher Education “ Saratov Medical University “REVIZ”
Abstract
In experiments on outbred albino rats, it was established that subacute intoxication with ethylene chlorohydrin (0.2 LD50 daily for 4 days) causes a decrease in Th1 and Th2 lymphocytes function to the same extent, diminishes parameters of humoral and cellular immune responses and the content of immunoregulatory cytokines IFN- , IL-2, IL-4 in blood, increases concentrations of pro-inflammatory cytokine IL-6 and anti-inflammatory cytokine IL-10.
Publisher
Russian Register of Potentially Hazardous Chemical and Biological Substances
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