Animal models of necrotizing enterocolitis: review of the literature and state of the art-Reference-Cited by-同舟云学术

Animal models of necrotizing enterocolitis: review of the literature and state of the art

Published:2018-03-10 Issue:2 Volume:3 Page:87-92
ISSN:2364-7485
Container-title:Innovative Surgical Sciences
language:
Short-container-title:

Author:

Sulistyo Adrienne¹,Rahman Abidur¹,Biouss George¹,Antounians Lina¹,Zani Augusto²

Affiliation:

1. Division of General and Thoracic Surgery, Developmental and Stem Cell Biology Program, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, University of Toronto, 1524C-555 University Avenue, Toronto, ON M5G 1X8, Canada

2. Division of General and Thoracic Surgery, Developmental and Stem Cell Biology Program, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, University of Toronto, 1524C-555 University Avenue, Toronto, ON M5G 1X8, Canada, Phone: +1-416-813-7564 ext. 202413

Abstract

AbstractNecrotizing enterocolitis (NEC) remains the leading cause of gastrointestinal surgical emergency in preterm neonates. Over the last five decades, a variety of experimental models have been developed to study the pathophysiology of this disease and to test the effectiveness of novel therapeutic strategies. Experimental NEC is mainly modeled in neonatal rats, mice and piglets. In this review, we focus on these experimental models and discuss the major advantages and disadvantages of each. We also briefly discuss other models that are not as widely used but have contributed to our current knowledge of NEC.

Publisher

Walter de Gruyter GmbH

Subject

Surgery

Link

https://www.degruyter.com/document/doi/10.1515/iss-2017-0050/pdf

Reference94 articles.

1. Experimental production of necrotizing enterocolitis in new-born goats;Pediatric Research,1974

2. The microenvironment influences the pattern of bacterial translocation in formula-fed neonates;J Pediatr Surg,1996

3. Phosphatidylinositol 3-kinase pathway regulates hypoxia-inducible factor-1 to protect from intestinal injury during necrotizing enterocolitis;Surgery,2007

4. Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993–2012;J Am Med Assoc,2015

5. Necrotizing enterocolitis: controversies and challenges;F1000Res,2015

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Immunological aspects of necrotizing enterocolitis models: a review;Frontiers in Immunology;2024-07-22

2. Photoacoustic imaging for non-invasive assessment of biomarkers of intestinal injury in experimental necrotizing enterocolitis;Pediatric Research;2024-06-24

3. Experimental modeling of necrotic enterocolitis: A review;Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care;2023-12-20

4. In Vivo Modeling of Complicated Necrotizing Enterocolitis;Innovative Medicine of Kuban;2023-11-15

5. Intestine and brain TLR-4 modulation following N-acetyl-cysteine treatment in NEC rodent model;Scientific Reports;2023-05-22