Reactions of 3-amino-1,2,4-triazine with coupling reagents and electrophiles-Reference-Cited by-同舟云学术

Reactions of 3-amino-1,2,4-triazine with coupling reagents and electrophiles

Published:2022-01-01 Issue:1 Volume:28 Page:157-163
ISSN:2191-0197
Container-title:Heterocyclic Communications
language:en
Short-container-title:

Author:

Bvumbi Mpelegeng Victoria¹,Nemudzivhadi Anza Imanuel¹,Sengane Musiiwa Victoria¹,Moleele Simon Mnyakeni¹

Affiliation:

1. Department of Chemistry, Faculty of Science, Engineering and Agriculture, University of Venda , Private Bag X5050 , Thohoyandou 0950 , South Africa

Abstract

Abstract Analogs of a new heterocyclic system were obtained from the reactions of 3-amino-1,2,4-triazine with coupling reagents such as boronic acids, and terminal alkynes in the presence of a palladium catalyst. Other reactions such as amination of the triazine at position 5, followed by electrophilic reactions with phenyl isocyanates and benzoyl chlorides, were performed to form new monoureido and benzoylated compounds.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Link

https://www.degruyter.com/document/doi/10.1515/hc-2022-0149/pdf

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