Preventive Action of Phospholipids on Decomposition of Methyl 13-Hydroperoxyoctadecadienoate

Abstract

Abstract The effects of phosphatidylcholine, phosphatidyletha-nolamine and phosphatidylserine on the thermal decom­position of methyl 13-hydroperoxyoctadecadienoate were investigated in a chloroform/methanol mixture. Among the phospholipids tested, phosphatidylserine in­ hibited the thermal decomposition of methyl 13-hydro­ peroxyoctadecadienoate to about 30% after exposure to 60 °C for 48h wheareas only 10% remained in the absence of the phospholipid for the same heating period. Addition of eugenol with phosphatidylserine showed high synergistic activity which prevented the decomposition of the hydroperoxide to a higher extent under the same conditions. Phosphatidylserine was also found to inhibit iron -accelerated decomposition of methyl 13-hydroperoxyoctadecadienoate. Moreover, the decomposition of the hydroperoxide accelerated by ascorbic acid was effectively prevented by a combination of eugenol and phosphatidylserine.