Antagonizing leptin: current status and future directions-Reference-Cited by-同舟云学术

Antagonizing leptin: current status and future directions

Published:2014-05-01 Issue:5 Volume:395 Page:499-514
ISSN:1437-4315
Container-title:Biological Chemistry
language:
Short-container-title:

Author:

Zabeau Lennart,Peelman Frank,Tavernier Jan

Abstract

Abstract The adipocyte-derived hormone/cytokine leptin acts as a metabolic switch, connecting the body’s nutritional status to high energy consuming processes such as reproduction and immune responses. Inappropriate leptin responses can promote autoimmune diseases and tumorigenesis. In this review we discuss the current strategies to modulate leptin signaling and the possibilities for their use in research and therapy.

Publisher

Walter de Gruyter GmbH

Subject

Clinical Biochemistry,Molecular Biology,Biochemistry

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