To date the greenest method for the preparation of α-hydroxyphosphonates from substituted benzaldehydes and dialkyl phosphites-Reference-Cited by-同舟云学术

To date the greenest method for the preparation of α-hydroxyphosphonates from substituted benzaldehydes and dialkyl phosphites

Published:2017-01-01 Issue:2 Volume:6 Page:
ISSN:2191-9550
Container-title:Green Processing and Synthesis
language:
Short-container-title:

Author:

Keglevich György,Rádai Zita,Kiss Nóra Zsuzsa

Abstract

AbstractRecent synthetic methods for α-hydroxyphosphonates comprise a green, solvent-free accomplishment of the Pudovik reaction that was typically followed by extractions and recrystallization, or even by chromatography, or other operations. We now developed a general procedure applying 10% of triethylamine as the catalyst and a minimum quantity of acetone as the solvent, giving the products in a pure form after a reflux of 5–120 min following the addition of some

Publisher

Walter de Gruyter GmbH

Subject

Health, Toxicology and Mutagenesis,Industrial and Manufacturing Engineering,Fuel Technology,Renewable Energy, Sustainability and the Environment,General Chemical Engineering,Environmental Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/gps-2016-0125/pdf

Reference78 articles.

1. The Preparation of Dimethyl α -Hydroxyphosphonates and the Chemical Shift Non-Equivalence of Their Diastereotopic Methyl Ester Groups

2. Silica-Supported Tungstic Acid Catalyzed Synthesis and Antioxidant Activity of α-Hydroxyphosphonates

3. MgCl2/Et3N Base System as a New Catalyst for the Synthesis of α-Hydroxyphosphonate

4. Surface-Mediated Solid Phase Reactions: Preparation Of Diethyl 1-Hydroxyarylmethylphosphonates on the Surface of Magnesia

5. Surface-Mediated Solid Phase Reactions: Preparation Of Diethyl 1-Hydroxyarylmethylphosphonates on the Surface of Magnesia

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