5-Methylcytosin-Gehalt in Rattenerythroleukämie-Zellen nach Induktion mit Dimethylsulfoxid / 5-Methylcytosine Content in Erythroleucemic Cells of Rats after Induction with Dimethylsulfoxid-Reference-Cited by-同舟云学术

5-Methylcytosin-Gehalt in Rattenerythroleukämie-Zellen nach Induktion mit Dimethylsulfoxid / 5-Methylcytosine Content in Erythroleucemic Cells of Rats after Induction with Dimethylsulfoxid

Published:1982-09-01 Issue:9 Volume:37 Page:812-817
ISSN:1865-7125
Container-title:Zeitschrift für Naturforschung C
language:en
Short-container-title:

Author:

Baur R.¹,Kluge N.²,Kröger H.¹,Wohlert H.¹

Affiliation:

1. Robert Koch-Institut Berlin, Abt. Biochemie, Nordufer 20, D-1000 Berlin 65

2. Institut für Physiologische Chemie der Universität Hamburg, Molekularbiologie, Grindelallee 117, IV, D-2000 Hamburg 13

Abstract

Erythroleucemic cells of rats were induced by DMSO for the terminal erythroid differentiation. The base composition and the 5MC content of the DNA were analyzed by HPLC and a significant difference between non-induced and induced cells was not found. The analysis of labelled DNA by the restriction enzymes Hha I, Hpa II, and Msp I did not result in a different pattern before and after the induction. These results suggest that the 5 MC content of the DNA does not change during the induced terminal erythroid differentiation.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.degruyter.com/document/doi/10.1515/znc-1982-0913/pdf

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Enzymatic DNA Methylation;Progress in Clinical Biochemistry and Medicine;1989

2. Influence of streptozotocin upon the induction of tyrosine aminotransferase, the content of NAD and of 5-methyl cytosine in rat liver;International Journal of Biochemistry;1986-01