Metallkomplexe mit biologisch wichtigen Liganden, CXX [1]. Halbsandwich-Komplexe von Ruthenium(II) und Iridium(III) mit 3-(3-Pyridyl)-D-alaninat

Abstract

The reactions of the chloro bridged complexes [(ρ-cymene)RuCl2]2 and [(C5Me5)IrCl2]2 with the anion of 3-(3-pyridyl)-D-alanine (L) afford the N,O-chelate complexes (p-cymene)- Ru(L)(Cl) (1) and (C5Me5)Ir(L)(Cl) (2). Abstraction of chloride from 1 and 2 using AgSbF6 gives the dimers [(ρ-cymene)Ru(μ-L)2Ru(ρ-cymene)]2+(SbF6)2 (3) and [(C5Me5)Ir(μ-L)2- Ir(C5Me5)]2+(SbF6)2 (4) with coordination of the pyridine N atom. Complex 4 is formed in high diastereomeric excess. The structure of (C5Me5)Ir(μ-L)2Ir(C5Me5)]Cl2 (5) which contains the SIrRCRC RIr diastereoisomer in the crystal was determined by X-ray diffraction.