Bridging the divide: addressing discrepancies between clinical guidelines, policy guidelines, and biomarker utilization-Reference-Cited by-同舟云学术

Bridging the divide: addressing discrepancies between clinical guidelines, policy guidelines, and biomarker utilization

Published:2024-08-01 Issue: Volume: Page:
ISSN:2194-8011
Container-title:Diagnosis
language:en
Short-container-title:

Author:

Horgan Denis¹²,Hofman Paul³,Buttner Reinhard⁴,Rieß Olaf⁵,Lugowska Iwona⁶,Dube France⁷,Singh Jaya¹,Nadal Ernest⁸,Stokłosa Tomasz⁹,Sīviņa Elīna¹⁰,Van der Buckle Marc¹¹,Mosoiu Silvia¹²,Bertolaccini Luca¹³,Girard Nicolas¹⁴,Meerbeeck Jan Van¹⁵,Omar Imran¹⁶,Capoluongo Ettore D.¹⁷,Bielack Stefan¹⁸,Hills Tanya¹⁹,Baldwin David²⁰,Subbiah Vivek²¹

Affiliation:

1. European Alliance for Personalised Medicine , Brussels , Belgium

2. Department of Molecular and Cellular Engineering, Faculty of Engineering and Technology , Jacob Institute of Biotechnology and Bioengineering, Sam Higginbottom University of Agriculture, Technology and Sciences , Prayagraj , India

3. European Liquid Biopsy Society , Hamburg , Germany

4. Lung Cancer Group Cologne , Institute of Pathology and Medical Faculty, Center for Integrated Oncology Co-logne/Bonn, University Hospital Cologne , Cologne , Germany

5. Institute of Medical Genetics and Applied Genomics , University of Tuebingen , Tuebingen , Germany

6. Department of Soft Tissue/Bone Sarcoma and Melanoma , Maria Sklodowska-Curie National Research Institute and Oncology Centre (MSCI) , Warsaw , Poland

7. Astra Zeneca, Concord Pike , Wilmington , DE , USA

8. Catalan Institute of Oncology, University of Barcelona , Barcelona , Spain

9. University Clinical Center, Medical University of Warsaw , Warsaw , Poland

10. Tumour Clinical Research Department , Institute of Oncology, Riga Stradins University , Riga , Latvia

11. Belgian Cancer Centre , Sciensano , Brussels , Belgium

12. Oncology Department , University of Medicine and Pharmacy “Carol Davila” Bucharest , Bucharest , Romania

13. Department of Thoracic Surgery , IEO, European Institute of Oncology IRCCS , Milan , Italy

14. Claude Bernard University Lyon 1 , Villeurbanne , France

15. Department of Thoracic Oncology , MOCA, University Hospital Antwerp , Antwerp , Belgium

16. Academic Urology Unit , University of Aberdeen , Aberdeen , UK

17. Department of Clinical Pathology and Genomics , Azienda Ospedaliera Per L’Emergenza Cannizzaro , Catania , Italy

18. Department of Pediatric Oncology, Hematology, Immunology , Stuttgart Cancer Center, Olgahospital , Stuttgart , Germany

19. Boehringer Ingelheim International GmbH , Ingelheim am Rhein , Germany

20. Institute of War & Peace Studies , Columbia University , New York , NY , USA

21. Sarah Cannon Research Institute , Nashville , TN , USA

Abstract

Abstract Objectives This paper aims to identify and address gaps in cancer treatment and diagnosis within European health services, focusing specifically on discrepancies between clinical guidelines and policy guidelines. It seeks to highlight how the underutilization of advanced diagnostic techniques recommended by medical societies contributes to missed opportunities for improving patient outcomes. Methods A comprehensive analysis was conducted across multiple European countries to assess the compliance and integration of clinical guidelines with the availability of advanced diagnostic technologies. Secondary data related to clinical and policy guidelines in cancer care were collected and analyzed. Key indicators of adoption and utilization of next-generation sequencing and liquid biopsy were examined to evaluate their impact on health service efficiency and patient care. Results The analysis revealed significant discrepancies between the recommendations of medical societies regarding advanced diagnostic techniques and their adoption in health policy decisions across Europe. Country-specific assessments indicated varying levels of alignment between clinical guidelines and the availability of advanced diagnostics. These findings underscored missed opportunities for optimizing patient care and health service efficiency through better alignment and integration of clinical guidelines with policy decisions. Conclusions This study concludes that there is a critical need for health policy decision-makers to prioritize the adoption of clinical guidelines in resource allocation and health service organization. Greater attention to the recommendations of medical societies regarding advanced diagnostic techniques could significantly enhance diagnostic accuracy, treatment efficacy, and overall patient outcomes in cancer care. The paper advocates for policy reforms that acknowledge and leverage the potential benefits of advanced diagnostics in improving health service performance and patient-centered care across Europe.

Publisher

Walter de Gruyter GmbH

Link

https://www.degruyter.com/document/doi/10.1515/dx-2024-0092/pdf

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