Hyphenated differential mobility spectrometry for rapid separation and detection

Author:

Yang Liu,Han Qiang,Cao Shuya1,Yang Junchao1,Zhao Jiang1,Ding Mingyu2

Affiliation:

1. 1State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China

2. 2Beijing Key Laboratory for Microanalytical Methods and Instrumentation, Department of Chemistry, Tsinghua University, Beijing 100084, China

Abstract

AbstractThis paper reviews hyphenated differential mobility spectrometry (DMS) technology. DMS is a type of ion mobility spectrometry (IMS) also called high-field asymmetric waveform IMS. It is widely used in the detection of chemical warfare agents, explosives, drugs, and volatile organic compounds. Stand-alone DMS analysis of complex mixtures in real-field applications is challenging. Hyphenated DMS can improve resolution for rapid separation and detection. This review focuses on hyphenated DMS, including gas chromatography-DMS, DMS-mass spectrometry (MS), DMS-IMS, IMS-DMS, and DMS-DMS, as well as their associated principles, applications, and research procedures. Key problems in hyphenated DMS are considered.

Publisher

Walter de Gruyter GmbH

Subject

Analytical Chemistry

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