Affiliation:
1. 201430 Instituto de Química Orgánica General , CSIC , Madrid , Spain
Abstract
Abstract
The amide bond is one of the most important structural units in nature, as it is part of the backbone of peptides and natural proteins, as well as some essential amino acids, DNA, RNA, hormones, or vitamins found in the body. Furthermore, this bond is significant in the pharmaceutical industry due to its presence in the structure of numerous APIs contained in drugs. This paper reviews the most important methods collected in the bibliography for the preparation of this moiety.
Reference36 articles.
1. J.R. Dunetz, J. Magano, G.A. Weisenburger. Org. Proc. Res. Dev. 20, 140 (2016), https://doi.org/10.1021/op500305s.
2. L. Zhu, L. Deng, Y. Xie, L. Liu, X. Ma, R. Liu. Results Chem. 5, 100882 (2023), https://doi.org/10.1016/j.rechem.2023.100882.
3. Guidelines for Authors of the American Chemical Society, A.M. Coghill, L.R. Garson. The ACS Stile Guide: Effective Communication of Scientific Information, pp. 169–202, Oxford University Press, New York (2006).
4. A. El-Faham, F. Albericio. Chem. Rev. 111, 6557 (2011), https://doi.org/10.1021/cr100048w.
5. C.A.N.G. Montalbetti, V. Falque. Tetrahedron 61, 10827 (2005), https://doi.org/10.1016/j.tet.2005.08.031.