Author:
Baldwin Nigel C. P.,Bycroft Barrie W.,Dewick Paul M.,Gilbert John,Holden Ian
Abstract
Abstract
A high yielding production of the trichothecene mycotoxin 3-acetyldeoxynivalenol (3-AcDON) in cultures of Fusarium culmorum is described. By supplying [14C]acetate, 14C-labelled 3-AcDON suitable for further metabolic studies has been obtained. The pattern of labelling has been ascertained by using 13C-labelled acetate precursors, and is in line with established biosynthetic data. A second trichothecene produced in significant amounts by F. culmorum has been identified as 3α, 15-diacetoxy-7α, 8α-dihydroxy-12, 13-epoxytrichothec-9-ene (7α, 8α-dihydroxycalonec-trin).
Subject
General Biochemistry, Genetics and Molecular Biology
Cited by
11 articles.
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