A new targetry system for production of zirconium-89 radioisotope with Cyclone-30 cyclotron
Author:
Feizi Shahzad1, Fazaeli Yousef1, Ashtari Parviz1, Shirmardi Seyed Pezhman1, Yousefnia Hasan1, Aslani Gholamreza1
Affiliation:
1. Radiation Application Research School, Nuclear Science and Technology Research Institute (NSTRI) , Moazzen Blvd., Rajaeeshahr, P.O. Box 31485-498 , Karaj , Iran
Abstract
Abstract
In this study, an efficient method for targetry and production of zirconium-89 radioisotope (89Zr) with Cyclone-30 cyclotron was developed. The preparation of a highly pure compressed yttrium oxide target material and design of a target made by copper for better heat transfer was performed. Electrodeposition of target with gold was done to prevent the entry of metallic impurities (copper, zinc and other trace metal elements). Nuclear reaction cross sections for optimization of production with new target and irradiation parameters of the target were evaluated. The prepared 89Zr in the form of [89Zr] Zr-oxalate had high radionuclidic purity (>99.9%) and a low chemical impurity concentration (<0.1 ppm for copper and zinc elements). The yield of 89Zr radioisotope production via the reaction of 89Y(p,n)89Zr was measured to be 77 ± 9.5 MBq/μAh (time of irradiation = 3, the current 20–30 µA). [89Zr] Zr-oxalate specific-activity was in the range 2.319641 × 104–3.479443 × 104 MBq/mmol of Oxalate.
Publisher
Walter de Gruyter GmbH
Subject
Physical and Theoretical Chemistry
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