A review of the pharmacological activities and protective effects of <i>Inonotus obliquus</i> triterpenoids in kidney diseases-Reference-Cited by-同舟云学术

A review of the pharmacological activities and protective effects of Inonotus obliquus triterpenoids in kidney diseases

Published:2022-01-01 Issue:1 Volume:20 Page:651-665
ISSN:2391-5420
Container-title:Open Chemistry
language:en
Short-container-title:

Author:

Tian Lingling¹,Wang Yi¹,Qing Jianbo²³,Zhou Wenjing⁴,Sun Lin⁵,Li Rongshan⁶⁷,Li Yafeng²⁸⁹¹⁰

Affiliation:

1. The Third Clinical College, Shanxi University of Chinese Medicine , Taiyuan , Shanxi, 030001 , China

2. Department of Nephrology, Shanxi Provincial People’s Hospital (Fifth Hospital) of Shanxi Medical University , Taiyuan , 030001 , China

3. The Fifth Clinical Medical College of Shanxi Medical University , Taiyuan , Shanxi, 030001 , China

4. School of Medical Sciences, Shanxi University of Chinese Medicine , jinzhong , 030619 , China

5. College of Taditional Chinese Medicine and Food Engineering, Shanxi University of Chinese Medicine , jinzhong , 030619 , China

6. Department of Nephrology, Shanxi Provincial People’s Hospital (Fifth Hospital) of Shanxi Medical University ; Taiyuan , 030001 , China

7. Shanxi Provincial Key Laboratory of Kidney Disease, Shanxi Provincial People’s Hospital (Fifth Hospital) of Shanxi Medical University , Taiyuan, 030012 , Shanxi , China

8. Shanxi Provincial Key Laboratory of Kidney Disease, Shanxi Provincial People’s Hospital (Fifth Hospital) of Shanxi Medical University , Taiyuan , 030012, Shanxi , China

9. Core Laboratory, Shanxi Provincial People’s Hospital (Fifth Hospital) of Shanxi Medical University , Taiyuan , 030001 , China

10. Academy of Microbial Ecology, Shanxi Medical University , Taiyuan , 030001 , China

Abstract

Abstract Kidney diseases are common health problems worldwide. Various etiologies ultimately lead to the development of chronic kidney disease and end-stage renal disease. Natural compounds from herbs or medicinal plants are widely used for therapy and prevention of various ailments, among which is Inonotus obliquus. I. obliquus is rich in triterpenoids and the main active ingredients include betulinic acid, trametenolic acid, inotodiol, and ergosterol. New evidence suggests that I. obliquus triterpenes may be an effective drug for the treatment and protection of various kidney diseases. The aim of this review is to highlight the pharmacological activities and potential role of I. obliquus triterpenes in the kidney disease treatment and protection.

Publisher

Walter de Gruyter GmbH

Subject

Materials Chemistry,General Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/chem-2022-0168/pdf

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