Novel synthesis and reactions of pyrazolyl-substituted tetrahydrothieno[2,3-c]isoquinoline derivatives-Reference-Cited by-同舟云学术

Novel synthesis and reactions of pyrazolyl-substituted tetrahydrothieno[2,3-c]isoquinoline derivatives

Published:2016-04-01 Issue:2 Volume:22 Page:103-109
ISSN:2191-0197
Container-title:Heterocyclic Communications
language:
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Author:

Zaki Remon M.¹,El Dean Adel M. Kamal²,El Monem Maisa I. Abd²,Seddik Mohamed A.²

Affiliation:

1. 1Chemistry Department, Faculty of Science, Assiut University, 71516, Assiut, Egypt, rasal@aun.edu.eg

2. 2Chemistry Department, Faculty of Science, Assiut University, 71516, Assiut, Egypt

Abstract

AbstractTreatment of isoquinolinecarboxamide 4a with triethyl orthoformate, chloroacetyl chloride or carbon disulfide afforded the pyrimidinone 7, oxopyrimidinethione 12 and chloromethylpyrimidinone 18, respectively. These products were used as versatile starting materials for synthesis of other heterocyclic compounds. The heterocyclic hydrazide 6 was also obtained.

Publisher

Walter de Gruyter GmbH

Subject

Organic Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/hc-2015-0204/pdf

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