Author:
Mandigers Loes,Bollen Pauline D.J.,Bijlstra Peter J.,Brands Els
Abstract
AbstractWe report a case of an adult patient using chronic low-dose verapamil who developed severe verapamil intoxication. A 57-year-old male patient was presented at the emergency room after a collapse of unknown etiology. The airway was compromised, and thus, an endotracheal tube was inserted. The patient deteriorated hemodynamically. Because of verapamil use and bradycardia, verapamil intoxication was suspected. The treatment was supported with intravenous fluids, calcium, inotropes, and a transvenous pacemaker. The patient progressively developed circulatory shock. Verapamil intoxication was confirmed, and therapy was adjusted accordingly. Insulin and calcium infusion were intensified, and glucagon and Intralipid
Subject
Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics
Reference18 articles.
1. Non cardiogenic pulmonary oedema in course of verapamil intoxication;Sami Karti;Emerg Med,2002
2. Verapamil plus antiarrhythmic drugs reduce atrial fibrillation recurrences after an electrical cardioversion Study Hearts;De Simona;Eur,2003
3. Eichelbaum Cytochromes of the subfamily are the major enzymes involved in the demethylation of verapamil in humans - Schmiedeberg s Arch;Busse;Pharmacol,1995
4. Acute intoxication with verapamil;Candell;Chest,1979
5. Acute verapamil toxicity in a patient with chronic toxicity : possible interaction with ceftriaxone and clindamycin;Kishore;Ann Pharmacother,1993
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