The intricate role of glutamine in pathophysiological contexts
Author:
Affiliation:
1. Department of Clinical Medicine and Surgery , University of Naples “Federico II” , Naples , Italy
Publisher
Walter de Gruyter GmbH
Subject
Drug Discovery,Pharmacology,General Medicine,Physiology
Link
https://www.degruyter.com/document/doi/10.1515/jbcpp-2023-0179/pdf
Reference24 articles.
1. Lee, JS, Adler, L, Karathia, H, Carmel, N, Rabinovich, S, Auslander, N, et al.. Urea cycle dysregulation generates clinically relevant genomic and biochemical signatures. Cell 2018;174:1559–70 e22. https://doi.org/10.1016/j.cell.2018.07.019.
2. Cruzat, V, Rogero, MM, Keane, KN, Curi, R, Newsholme, P. Glutamine: metabolism and immune function, supplementation and clinical translation. Nutrients 2018;10:1564. https://doi.org/10.3390/nu10111564.
3. Xiao, D, Zeng, L, Yao, K, Kong, X, Wu, G, Yin, Y. The glutamine-alpha-ketoglutarate (AKG) metabolism and its nutritional implications. Amino Acids 2016;48:2067–80. https://doi.org/10.1007/s00726-016-2254-8.
4. Smith, B, Schafer, X, Ambeskovic, A, Spencer, C, Land, H, Munger, J. Addiction to coupling of the warburg effect with glutamine catabolism in cancer cells. Cell Rep 2016;17:821–36. https://doi.org/10.1016/j.celrep.2016.09.045.
5. Bose, S, Le, A. Glucose metabolism in cancer. Adv Exp Med Biol 2018;1063:3–12. https://doi.org/10.1007/978-3-319-77736-8_1.
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