Design, Synthesis and Antifungal Activity of the Novel Water-Soluble Prodrug of Antifungal Triazole CS-758-Reference-Cited by-同舟云学术

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Design, Synthesis and Antifungal Activity of the Novel Water-Soluble Prodrug of Antifungal Triazole CS-758

Published:2010 Issue:6 Volume:58 Page:794-804
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

Kagoshima Yoshiko¹,Mori Makoto²,Suzuki Eiko³,Kobayashi Nobue³,Shibayama Takahiro³,Kubota Mikie⁴,Kamai Yasuki⁴,Konosu Toshiyuki¹

Affiliation:

1. Medicinal Chemistry Research Laboratories II, Daiichi Sankyo Co., Ltd.

2. Medicinal Chemistry Research Laboratories I, Daiichi Sankyo Co., Ltd.

3. Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd.

4. Biological Research Laboratories IV, Daiichi Sankyo Co., Ltd.

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

http://www.jstage.jst.go.jp/article/cpb/58/6/58_6_794/_pdf

Reference22 articles.

1. 2) Saxena S., Khan J. A., Ghosh P. C., J. Antimicrob. Chemother., 42, 635—642 (1998).

2. 3) Petit C., Cheron M., Joly V., Rodrigues J. M., Bolard J., Gaboriau F., J. Antimicrob. Chemother., 42, 779—785 (1998).

3. Nonclinical studies and clinical studies on fosfluconazole, a triazole antifungal agent (Prodif®)

4. The Discovery and Process Development of a Commercial Route to the Water Soluble Prodrug, Fosfluconazole

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