Estimating Pediatric Doses of Drugs Metabolized by Cytochrome P450 (CYP) Isozymes, Based on Physiological Liver Development and Serum Protein Levels

Author:

SUZUKI Shinya12,MURAYAMA Yuka1,SUGIYAMA Erika1,HIRUNPANICH Vilasinee3,SAITO Kiyomi1,SEKIYAMA Masao2,SATO Hitoshi1

Affiliation:

1. Department of Clinical and Molecular Pharmacokinetics/Pharmacodynamics, School of Pharmaceutical Sciences, Showa University

2. Department of Pharmacy, Kanagawa Prefectural Keiyukai Keiyu Hospital

3. Faculty of Pharmacy, Mahasarakham University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology

Reference22 articles.

1. 1) Suzuki S., Murayama Y., Sugiyama E., Sekiyama M., Sato H., YAKUGAKU ZASSHI, 129, 829-842 (2009).

2. 2) Suzuki S., Murayama Y., Sugiyama E., Sekiyama M., Sato H., Jpn. J. Pharm. Health Care Sci., 35, 791-798 (2009).

3. 3) Johnson T. N., Rostami-Hodjegan A., Tucker G. T., Clin. Phamacokinet., 45, 931-956 (2006).

4. 4) Investigation Report on Physical Development of Infants and Early Children in 2000 (Ministry of Health and Labor, Japan).

5. 5) Investigation Report on School Health Statistics in 2000 (Ministry of Education and Science, Japan).

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