Disulfiram Chelated with Copper Promotes Apoptosis in Osteosarcoma via ROS/Mitochondria Pathway
Author:
Affiliation:
1. Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University
2. Department of Hand Surgery, The First Affiliated Hospital of Wenzhou Medical University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/44/10/44_b21-00466/_pdf
Reference22 articles.
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2. 2) Isakoff MS, Bielack SS, Meltzer P, Gorlick R. Osteosarcoma: current treatment and a collaborative pathway to success. J. Clin. Oncol., 33, 3029–3035 (2015).
3. 3) Annesley SJ, Fisher PR. Mitochondria in health and disease. Cells, 8, 680 (2019).
4. 4) Yang Y, Karakhanova S, Hartwig W, D’Haese JG, Philippov PP, Werner J, Bazhin AV. Mitochondria and mitochondrial ROS in cancer: novel targets for anticancer therapy. J. Cell. Physiol., 231, 2570–2581 (2016).
5. 5) Zorov DB, Juhaszova M, Sollott SJ. Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. Physiol. Rev., 94, 909–950 (2014).
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