Adenosine A2A Receptor Agonist PSB-0777 Modulates Synaptic Proteins and AMPA Receptor Expression in a Dose- and Time-Dependent Manner in Rat Primary Cortical Neurons

Author:

Luo Shaolei1,Hou Yangyang1,Zhang Yaping1,Ma Tengfei2,Shao Wenping3,Xiao Chunjie1

Affiliation:

1. Yunnan University, School of Medicine

2. Yunnan University, School of Life Sciences, Center for Life Sciences

3. First Affiliated Hospital of Kunming Medical University, Department of Medical Examination

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference78 articles.

1. 1) Chen JF, Sonsalla PK, Pedata F, Melani A, Domenici MR, Popoli P, Geiger J, Lopes LV, de Mendonça A. Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and “fine tuning” modulation. Prog. Neurobiol., 83, 310–331 (2007).

2. 2) Sebastião AM, Ribeiro JA. Adenosine receptors and the central nervous system. Handb. Exp. Pharmacol., 193, 471–534 (2009).

3. 3) Masino SA, Kawamura M Jr, Ruskin DN. Adenosine receptors and epilepsy: current evidence and future potential. Int. Rev. Neurobiol., 119, 233–255 (2014).

4. 4) Cunha RA. How does adenosine control neuronal dysfunction and neurodegeneration? J. Neurochem., 139, 1019–1055 (2016).

5. 5) Svenningsson P, Hall H, Sedvall G, Fredholm BB. Distribution of adenosine receptors in the postmortem human brain: an extended autoradiographic study. Synapse, 27, 322–335 (1997).

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