FOXA1 Induces E-Cadherin Expression at the Protein Level via Suppression of Slug in Epithelial Breast Cancer Cells

Author:

Anzai Erina1,Hirata Kensuke1,Shibazaki Misato1,Yamada Chiaki1,Morii Mariko1,Honda Takuya1,Yamaguchi Naoto1,Yamaguchi Noritaka1

Affiliation:

1. Laboratory of Molecular Cell Biology, Graduate School of Pharmaceutical Sciences, Chiba University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference24 articles.

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2. 2) De Craene B, Berx G. Regulatory networks defining EMT during cancer initiation and progression. Nat. Rev. Cancer, 13, 97–110 (2013).

3. 3) Fischer KR, Durrans A, Lee S, Sheng J, Li F, Wong ST, Choi H, El Rayes T, Ryu S, Troeger J, Schwabe RF, Vahdat LT, Altorki NK, Mittal V, Gao D. Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance. Nature, 527, 472–476 (2015).

4. 4) Zheng X, Carstens JL, Kim J, Scheible M, Kaye J, Sugimoto H, Wu CC, LeBleu VS, Kalluri R. Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature, 527, 525–530 (2015).

5. 5) Lamouille S, Xu J, Derynck R. Molecular mechanisms of epithelial–mesenchymal transition. Nat. Rev. Mol. Cell Biol., 15, 178–196 (2014).

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