MODERN METHODS OF DIAGNOSIS AND TREATMENT OF CHRONIC ENDOMETRITIS, IN PREPARING PATIENTS FOR ASSISTED REPRODUCTIVE TREATMENT TECHNOLOGIES (LIT ERATURE REVIEW)

Author:

Chalova L.1ORCID,Lokshin V.2ORCID,Orazov M.3ORCID,Rybina A.4ORCID,Kim T.5ORCID,Kinzhibayev A.6ORCID

Affiliation:

1. reproductive medicine and fertility specialist, obstetrician and gynaecologist, Director of LLP Health and Science Сenter "М1", Nur-Sultan, Kazakhstan, lsaat@mail.ru, https://orcid.org/0000-0003-3040-3751

2. PhD, professor, Director of ICCR "PERSONA", Almaty, Kazakhstan; v_lokshin@persona-ivf.kz; https://orcid.org/0000-0002-4792-5380;

3. MD, Professor at the Department of obstetrics and gynecology with course of Perinatology of the PFUR, Moscow, Russia; omekan@mail.ru. https://orcid.org/0000-0002-1767-5536

4. reproductive medicine and fertility specialist, obstetrician and gynaecologist of ICCR "PERSONA", Almaty, Kazakhstan; oedema@mail.ru; https://orcid.org/0000-0002-9368-6683

5. PhD, reproductive medicine and fertility specialist, obstetrician and gynaecologist of LLP Health and Science Сenter "M1", Nur-Sultan, Kazakhstan, kimtv_12@mail.ru, https://orcid.org/0000-0001-9964-9042;

6. clinical embryologist of LLP Health and Science Сenter "M1", Nur-Sultan, Kazakhstan; kinzhibay@gmail.com; https://orcid.org/0000-0002-1752-0964

Abstract

Since the chronic endometritis often leads to impaired reproductive function causing infertility, failed IVF attempts, miscarriage, and complicated pregnancy and childbirth, it has become not only medically relevant but also socially significant. For successful embryo implantation, the thickness of the endometrium should be at least 7 cm. Even though there is always a chance for embryo implantation, despite the endometrial hypoplasia, the attachment may be fragile, and such pregnancy may cease its development further on. Recently, in connection with an increase in the rate of developing allergic reactions, dysbacteriosis, and the emergence of drug-resistant strains of microorganisms, a search for new treatment methods to avoid these complications has begun. One of such methods in treating chronic endometritis, satisfying several requirements (efficiency, comfort, accessibility, safety), is the ultrasonic cavitation of the uterine cavity.

Publisher

National Academy of Sciences of the Republic of Kazakshtan

Subject

General Medicine

Reference59 articles.

1. World health statistics. Geneva, WHO, 2011

2. Nazarenko T.A. Stimulation of ovarian function/T.A. Nazarenko. M.: MEDpress-inform, 2015. p. 288.

3. Volkov N.I. Clinical picture, diagnosis and treatment of infertility in women with external genital endometriosis//Paths of development of modern gynecology: thesis. M., 1995. p. 159.

4. Clinical practice in reproductive medicine / Edited by V.N. Lokshina, T.M. Dzhusubalieva. Almaty: MedMedia Kazakhstan, 2015. p. 464.

5. Rudakova E.B., Mozgovoy S.I., Pilipenko M.A. et al. Chronic endometritis: from improving the diagnostic approach to optimizing treatment // Attending physician. 2008. No. 10. p. 6-10.

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