The impact of assay technology as applied to safety assessment in reducing compound attrition in drug discovery
Author:
Publisher
Informa Healthcare
Subject
Drug Discovery
Link
http://www.tandfonline.com/doi/pdf/10.1517/17460441.2012.651122
Reference56 articles.
1. Navigating chemical space for biology and medicine
2. Computer systems for the prediction of toxicity: an update
3. Use of the Miniscreen assay to screen novel compounds for bacterial mutagenicity in the pharmacentical industry
4. In vivo mutation assay based on the endogenousPig-a locus
5. High-Content Micronucleus Assay in Genotoxicity Profiling: Initial-Stage Development and Some Applications in the Investigative/Lead-Finding Studies in Drug Discovery
Cited by 23 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Expanding Predictive Capacities in Toxicology: Insights from Hackathon-Enhanced Data and Model Aggregation;Molecules;2024-04-17
2. Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures;J CHEM INF MODEL;2023
3. Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures;Journal of Chemical Information and Modeling;2023-03-27
4. Predictive in vitro toxicology screening to guide chemical design in drug discovery;Current Opinion in Toxicology;2019-06
5. Using Human Pluripotent Stem Cell-Derived Neural Cultures to Assess Safety of New Drugs and Chemicals;Neurotoxins;2018-05-23
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3