Judging the value of ‘liver-on-a-chip’ devices for prediction of toxicity-Reference-Cited by-同舟云学术

Judging the value of ‘liver-on-a-chip’ devices for prediction of toxicity

Published:2016-10-18 Issue:2 Volume:13 Page:125-128
ISSN:1742-5255
Container-title:Expert Opinion on Drug Metabolism & Toxicology
language:en
Short-container-title:Expert Opinion on Drug Metabolism & Toxicology

Author:

Starokozhko Viktoriia¹,Groothuis Geny M. M.¹

Affiliation:

1. Division of Pharmacokinetics, Toxicology and Targeting, Groningen Research Institute for Pharmacy, University of Groningen, Groningen, The Netherlands

Funder

University of Groningen

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/17425255.2017.1246537

Reference14 articles.

1. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

2. Predictive toxicology using systemic biology and liver microfluidic “on chip” approaches: Application to acetaminophen injury

3. Real-time monitoring of oxygen uptake in hepatic bioreactor shows CYP450-independent mitochondrial toxicity of acetaminophen and amiodarone

4. On-line HPLC Analysis System for Metabolism and Inhibition Studies in Precision-Cut Liver Slices

5. Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution ofin-vitroliver technologies

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