Genetic variation in organic cation transporters and considerations in drug development-Reference-Cited by-同舟云学术

Genetic variation in organic cation transporters and considerations in drug development

Published:2023-03-04 Issue:3 Volume:19 Page:149-164
ISSN:1742-5255
Container-title:Expert Opinion on Drug Metabolism & Toxicology
language:en
Short-container-title:Expert Opinion on Drug Metabolism & Toxicology

Author:

Varma Manthena V. S.¹

Affiliation:

1. Pharmacokinetics, Dynamics and Metabolism, Pfizer Inc, Groton, CT, USA

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/17425255.2023.2202813

Reference141 articles.

1. US FDA. In Vitro metabolism- and transporter-mediated drug-drug interaction studies guidance for industry. Center for Drug Evaluation and Research (CDER), Silver Spring MD. https://wwwfdagov/regulatory-information/search-fda-guidance-documents/vitro-drug-interaction-studies-cytochrome-p450-enzyme-and-transporter-mediated-drug-interactions, (2020).

2. Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants

3. Membrane transporters in drug development

4. Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption

5. Hepatic and Intestinal Drug Transporters: Prediction of Pharmacokinetic Effects Caused by Drug-Drug Interactions and Genetic Polymorphisms

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