VERITAC-2: a Phase III study of vepdegestrant, a PROTAC ER degrader, versus fulvestrant in ER+/HER2- advanced breast cancer

Author:

Hamilton Erika P1ORCID,Ma Cynthia2,Laurentiis Michelino De3,Iwata Hiroji4,Hurvitz Sara A56,Wander Seth A78,Danso Michael9,Lu Dongrui R10,Smith Julia Perkins11,Liu Yuan12,Tran Lana13,Anderson Sibyl14,Campone Mario15

Affiliation:

1. Breast Cancer Research Program, Sarah Cannon Research Institute, Nashville, TN 37203, USA

2. Medicine Department, Washington University School of Medicine, St Louis, MO 63110, USA

3. Department of Breast & Thoracic Oncology, Istituto Nazionale Tumori IRCCS “Fondazione G. Pascale,” Naples, 80131, Italy

4. Department of Medical Research & Developmental Strategy, Nagoya City University, Graduate School of Medical Sciences, Nagoya, 467-8601, Japan

5. Division of Hematology Oncology, Department of Medicine, UW Medicine, Seattle, WA 98195, USA

6. Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA

7. Division of Medical Oncology, Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA

8. Harvard Medical School, Boston, MA 02115, USA

9. Medical Oncology, Brock Cancer Center, Virginia Oncology Associates, Norfolk, VA 23502, USA

10. Biostatistics, Pfizer Inc., San Diego, CA 92121, USA

11. Clinical Development, Pfizer, Inc., New York, NY 10017, USA

12. Translational Oncology, Pfizer, Inc., San Diego, CA 92121, USA

13. Clinical Pharmacology, Pfizer, Inc., San Diego, CA 92121, USA

14. Clinical Research, Arvinas Operations, Inc., New Haven, CT 06511, USA

15. Medical Oncology Department, Institut de Cancérologie de l'Ouest Angers-Nantes, Angers, 49055, France

Funder

Pfizer, Inc.

Arvinas Estrogen Receptor, Inc.

Publisher

Informa UK Limited

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