Expression of drug-metabolizing enzymes, nuclear transcription factors and ABC transporters in Caco-2 cells
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/00498250310001614286
Reference43 articles.
1. [43] Measurement of steroid hydroxylation reactions by high-performance liquid chromatography as indicator of P450 identity and function
2. Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells
3. Cytokines influence mRNA expression of cytochrome P450 3A4 and MDRI in intestinal cells
4. Induction of nuclear transcription factors, cytochrome P450 monooxygenases, and glutathione S-transferase alpha gene expression in Aroclor 1254-treated rat hepatocyte cultures11Abbreviations: Ah, aryl hydrocarbon; c/EBP, CCAAT/enhancer-binding protein; cDNA, complementary DNA CYP, cytochrome P450; EROD, ethoxyresorufin-O-deethylase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GSTA, glutathione S-transferase alpha; HNF, hepatic nuclear factor; RT–PCR, reverse transcription–polymerase chain reaction; and TF, transcription factor.
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