AMPA receptors and perampanel behind selected epilepsies: current evidence and future perspectives

Author:

Di Bonaventura Carlo1,Labate Angelo23,Maschio Marta4,Meletti Stefano5,Russo Emilio6

Affiliation:

1. Department of Neurology and Psychiatry, Neurology Unit, ‘Sapienza’ University, Rome, Italy

2. Institute of Neurology, University Magna Graecia of Catanzaro, Catanzaro, Italy

3. Institute of Molecular Bioimaging and Physiology of the National Research Council, Catanzaro, Italy

4. Center for Tumor-related Epilepsy, UOSD Neurology, Regina Elena National Cancer Institute, Rome, Italy

5. Department of Biomedical, Metabolic and Neural Sciences, Center for Neuroscience and Neurotechnology, University of Modena and Reggio Emilia, Modena, Italy

6. Department of Science of Health, School of Medicine and Surgery, University ‘Magna Graecia’ of Catanzaro, Catanzaro, Italy

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference101 articles.

1. Revisiting AMPA Receptors as an Antiepileptic Drug Target

2. Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist

3. Fycompa Summary of Product Characteristics. [cited 2017 Jul 20]. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002434/WC500130815.pdf

4. Molecular targets for antiepileptic drug development

5. New AMPA antagonists in epilepsy

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