1. Department of Clinical and Experimental Medicine, Clinical Unit for Chronic Bowel Disorders, University of Messina, Messina, Italy
2. Unit of Biostatistics, Fondazione IRCCS Casa Sollievo della Sofferenza, Foggia, Italy
3. Italian Society of General Medicine (SIMG), Section Messina, Messina, Italy
4. Department of Economics, University of Messina, Messina, Italy
5. Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy