Validation studies for germ-free Smad3-/- mice as a bio-assay to test the causative role of fecal microbiomes in IBD
Author:
Affiliation:
1. The Department of Comparative Medicine, University of Washington, Seattle, WA, USA
Funder
CCSG pilot award from the NIH/NCI Cancer Center Support
Publisher
Informa UK Limited
Subject
Infectious Diseases,Microbiology (medical),Gastroenterology,Microbiology
Link
https://www.tandfonline.com/doi/pdf/10.1080/19490976.2019.1611151
Reference35 articles.
1. Ablation of Tumor Necrosis Factor Is Associated with Decreased Inflammation and Alterations of the Microbiota in a Mouse Model of Inflammatory Bowel Disease
2. Microbial imbalance and intestinal pathologies: connections and contributions
3. Animal models to study acute and chronic intestinal inflammation in mammals
4. Helicobacter Infection Is Required for Inflammation and Colon Cancer in Smad3-Deficient Mice
5. Characterization of Dextran Sodium Sulfate-Induced Inflammation and Colonic Tumorigenesis in Smad3−/− Mice with Dysregulated TGFβ
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