Antioxidant and anti-inflammatory protective effects of rutin and kolaviron against busulfan-induced testicular injuries in rats
Author:
Affiliation:
1. Department of Biochemistry, University of Port Harcourt, Choba, Nigeria
2. Department of Chemistry/Biochemistry & Molecular Biology, Alex Ekwueme-Federal University Ndufu-Alike, Ikwo, Nigeria
Funder
funding agency
Publisher
Informa UK Limited
Subject
Urology,Reproductive Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/19396368.2021.1989727
Reference59 articles.
1. Kolaviron, a natural flavonoid from the seeds of Garcinia kola, reduces LPS-induced inflammation in macrophages by combined inhibition of IL-6 secretion, and inflammatory transcription factors, ERK1/2, NF-κB, p38, Akt, p-c-JUN and JNK
2. Anti-inflammatory effects of kolaviron modulate the expressions of inflammatory marker genes, inhibit transcription factors ERK1/2, p-JNK, NF-κB, and activate Akt expressions in the 93RS2 Sertoli cell lines
3. Combined administration of curcumin and gallic acid inhibits gallic acid-induced suppression of steroidogenesis, sperm output, antioxidant defenses and inflammatory responsive genes
4. Kolaviron protects apoptotic cell death in PC12 cells exposed to Atrazine
5. Kolaviron Biflavanoids of Garcinia Kola Seeds Protect Atrazine-Induced Cytotoxicity in Primary Cultures of Rat Leydig Cells
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